Down's syndrome

UK:**UK and possibly other pronunciationsUK and possibly other pronunciations/ˈdaʊnzˌsɪndrəʊm/US:USA pronunciation: IPAUSA pronunciation: IPA/ˈdaʊnz ˈsɪndroʊm/


WordReference Random House Learner's Dictionary of American English © 2026
Down's syn•drome /ˈdaʊnz ˈsɪndroʊm/USA pronunciation  n. [uncountable]
  1. PathologyAlso, Down syndrome. a condition from birth of mental retardation and the development of a flat forehead.

WordReference Random House Unabridged Dictionary of American English © 2026
Down's′ syn′drome, [Pathol.]
  1. PathologySee Down syndrome. 

Collins Concise English Dictionary © HarperCollins Publishers::
Down's syndrome, US Down syndrome n
  1. a condition caused by the presence of an extra copy of chromosome 21 resulting in learning difficulties and physical differences, such as shorter statureTechnical name: trisomy 21
Etymology: 19th Century: after John Langdon-Down (1828–96), English physician
'Down's syndrome' also found in these entries (note: many are not synonyms or translations):
alpha-fetoprotein - mongolism - mongol - mongoloid - Down syndrome

Forum discussions with the word(s) "Down's syndrome" in the title:


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